The S&P 500 fell 0.77% to 1,500 in afternoon trading Thursday.
The Dow Jones Industrial Average was down 0.57% to 13,848, while the Nasdaq was off 1.20% to 3,127.
The yield on a 10-year treasury bond was 2.82% to 1.96%.
The price of gold rose 0.10% to $1,580 per ounce.
Shares of Irvine-based molecular diagnostic company CombiMatrix Corp. shot up 130% to $6 on an article from investor research site Seeking Alpha that offered high expectations for the company’s earnings report expected next week. CombiMatrix had a recent market value of $6.6 million.
Irvine-based CoreLogic Inc. was down about 5% to $27 for a market value of $2.6 billion. The company, which provides data and analytics for the real estate and mortgage industries, is expected to report fourth-quarter results after the market closes on Thursday.
Newport Beach-based agricultural products maker American Vanguard Corp. was down about 5% to $30 for a market value of $857 million. The basic material sector, which includes companies that find and process raw materials, was generally down in afternoon trading Thursday.
Shares of Irvine laser maker Newport Corp. rose about 9% to $16 for a market value of $613.3 million. Newport Corp. reported a fourth-quarter profit that beat Wall Street expectations, but missed on consensus estimates for revenue during the quarter.