The Nasdaq was down 0.04% to 1.21% in midday trading Monday, while the Dow Jones Industrial Average was off 0.49% to 13,279.
The S&P 500 fell 0.45% to 1,427.
The yield on a 10-year treasury bond was up 1.7% to 1.8%.
The price of gold rose 0.24% to $1,728 per ounce.
Shares of Anaheim-based drug maker Questcor Pharmaceuticals Inc. was up 4% to $26 for a market value of $1.6 billion.
Aliso Viejo-based drug maker Avanir Pharmaceuticals Inc. was down about 3% to $3 for a market value of $417 million.