The S&P 500 fell 0.51% to 1,419 in midday trading Wednesday.
The Nasdaq was down 0.72% to 2,991, while the Dow Jones Industrial Average was off 0.29% to 13,101.
The yield on a 10-year treasury bond fell 1.07% to 1.75%.
The price of gold rose 0.14% to $1,662 per ounce.
Shares of San Clemente-based ICU Medical Inc. were down about 2% to $61 for a market value of $894 million. The medical device maker’s shares were downgraded Monday by Zacks from “outperform” to “neutral.”
Newport Beach-based specialty chemicals maker American Vanguard Corp. rose about 3% to $31 for a market value of $874 million.