The S&P 500 rose 0.1% to 3,389.82 in midday trading Friday.
The Dow Jones Industrial Average increased 0.4% to 27,858.22, while the Nasdaq was up 0.2% to 11,288.68.
Crude oil slid 2.6% to $41.71.
Gold fell 0.1% to $1,945.50.
The yield on a 10-year Treasury bond was down 1.4% to 0.64%.
Irvine drug maker Spectrum Pharmaceuticals Inc. (Nasdaq: SPPI) was down 4.4% to $3.87 for a market cap of $563.7 million.
Other OC drug makers also seeing declines, included Tustin-based Avid Bioservices Inc. (Nasdaq: CDMO), which fell 3% to $8.28 for a market cap of $467.9 million. Urovant Sciences Ltd. (Nasdaq: UROV) of Irvine declined 5.6% to $7.90 for a market cap of $246.3 million.
Irvine developer FivePoint Holdings LLC (NYSE: FPH) was trading down 3.5% to $5 for a market capitalization of $741.6 million. The company’s shares are down about 26% since the start of the year.