The S&P 500 was down 0.4% in midday trading to 2,363.38.
The Dow Jones Industrial Average was down 0.3% to 20,826.27.
The NASDAQ dropped 0.4% to 5,852.11.
The yield on a 10-year Treasury bond fell 0.7% to 2.59%.
The price of gold was flat at $1,203.
Irvine-based Tilly’s Inc. dropped 10% to $9.04 and a $258 million market cap. The youth fashion retailer yesterday gave a downbeat forecast for its current quarter.
Peregrine Pharmaceuticals in Tustin fell 10% to 69 cents and a $177 million market cap. The development stage cancer drug maker yesterday reported a third quarter loss.