The S&P 500 was down 0.6% to 3,361.8 in midday trading Friday.
The Dow Jones Industrial Average fell 0.1% to 27,798.5.
The Nasdaq slumped 1.9% to 11,111.7.
Crude oil fell 3.4% to $37.40.
Gold was down 0.5% to $1,906.50.
The yield on a 10-year Treasury rose 3.7% to 0.7%.
Irvine-based Inari Medical Inc. (Nasdaq: NARI) fell 5% to $64.32 for a market cap of $3.1 billion.
Other medical device makers also trading down on Friday, include San Clemente-based Glaukos Corp. (NYSE: GKOS), which fell 0.7% to $49.50 for a market cap of $2.2 billion. Masimo Corp. (Nasdaq: MASI) of Irvine was down 0.7% to $234.75 for a market cap of $12.9 billion.
Irvine developer Five Point Holdings LLC (NYSE: FPH) was up 8.8% to $4.72 for a market cap of $689.7 million. The company, which was trading on slightly higher than average volume Friday, is down about 30% since the start of the year.
Irvine-based Tilly’s Inc. (NYSE: TLYS) rose 4% to $6.23, trading on volume higher than its daily average. The men’s and women’s retailer had a recent market cap of $185.8 million.