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Wednesday, Apr 8, 2026

OC500 2024: Mike Mussallem

MIKE MUSSALLEM  

FORMER CHAIRMAN, CEO 

EDWARDS LIFESCIENCES 

 

WHY: First and longtime CEO of Orange County’s largest medtech employer, with about 5K workers and 20K worldwide. The Irvine-based heart valve maker is OC’s most valuable public company in the healthcare sector, sporting a $41B market cap as of October. 

IN THE NEWS: Retired as executive chairman of the company in May after stepping down as CEO in 2023.  

NOTABLE: Last year, Business Journal named Mussallem its Businessperson of the Year in the health sector.  

QUOTABLE: “I’m proud of Edwards’ continued dedication in providing innovative technologies and solutions for patients fighting cardiovascular disease and also restoring the critically ill to health.” 

 

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