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Wednesday, Apr 8, 2026

Artificial Bone Maker Being Bought for $51M

IsoTis Inc., an Irvine maker of artificial bone material, said Tuesday it’s being acquired by Integra LifeSciences Holdings Corp. for $51 million.

The deal calls for IsoTis shareholders to receive $7.25 a share for each share they own from Plainsboro, N.J.-based Integra.

The deal also includes $1.7 million in debt. It’s scheduled to close in the fourth quarter, subject to IsoTis shareholder approval.

Integra, whose products include collagen-based implants for tissue repair and cranial stabilization devices, said buying IsoTis would enhance its product offerings, broaden its international presence and increase its sales.

IsoTis is set to become a wholly owned subsidiary of Integra. The combined company will have more than 2,000 workers and operations in North America and Europe.

IsoTis was formed in 2003 when Irvine-based GenSci Orthobiologics Inc. combined with Isotis SA, a Switzerland-based medical device maker. IsoTis operates out of GenSci’s former facility in Irvine.

The company started trading on Nasdaq in January after an exchange offer through which it bought 75% of the shares of Isotis SA.

Isotis said it wanted to be a U.S. traded company for easier access to capital and to align its listing with its primary market and operations base. Isotis had traded publicly in Switzerland.

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