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Tuesday, May 26, 2026

California Stem Cell to Be Bought by NeoStem

Irvine-based California Stem Cell Inc. said today that it was being acquired by NeoStem Inc. in a stock and cash deal that potentially could be worth $124 million.

California Stem Cell is developing stem cell therapies for cancer and other diseases. The company has one product in late-stage development: Melapuldencel-T, a stem cell treatment for melanoma, or skin cancer.

NeoStem is publicly traded and based in New York City. It plans to initiate a third-phase trial of Melapuldencel-T.

California Stem Cell was founded in 2005. Its current chief executive, Hans Keirstead, is a pioneer in the county’s stem-cell industry, including serving as a professor at the University of California, Irvine.

Keirstead said in a statement that California Stem Cell believed that NeoStem’s “deep expertise in scaled manufacturing, regulatory and clinical development will advance our programs significantly.”

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