The S&P 500 was down 0.1% to 3,508.06 in midday trading Friday.
The Dow Jones Industrial Average declined 0.2% to 28,327.86, while the Nasdaq increased 0.1% to 11,898.29.
Crude oil fell 4% to $37.23.
Gold rose 0.3% to $1,951.70.
The yield on a 10-year Treasury was up 5.7% to 0.82%.
Alteryx Inc. shares were off 18% to $119.20 as investors reacted to the company’s current quarter guidance of $146 million to $150 million, which missed consensus estimates. The Irvine-based data analytics software firm had a recent market cap of $7.9 billion
Medical device makers were generally up on Friday, led by STAAR Surgical Co. (Nasdaq: STAA). The Lake Forest-based maker of implantable lenses rose 9.7% to $79.18 for a market cap of $3.7 billion.
Other movers include San Clemente-based Glaukos Corp. (NYSE: GKOS), up 8.7% to $61.40 for a market cap of $2.7 billion. Masimo Corp. of Irvine (Nasdaq: MASI) increased 3.3% to $258.31 for a market cap of $14 billion.