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Allergan Buys Eye Therapy Developer

Allergan Plc bought RetroSense Therapeutics for $60 million and milestone payments.

Allergan maintains a hub in Irvine for eyecare and aesthetics medicine product lines; its U.S. operations are in New Jersey and its corporate headquarters is in Ireland. It bought a glaucoma-treatment device developer in Menlo Park last month for $95 million plus milestones.

RetroSense in Ann Arbor, Mich., is developing a gene therapy to treat retinitis pigmentosa, with a follow-on indication for dry age-related macular degeneration.

The gene therapy is currently known as RST-001 and is the company’s lead candidate for future approval. It’s in pre-clinical stage and working toward human clinical trials.

Retinitis Pigmentosa is an inherited condition that produces gradual loss of vision from retinal degradation; dry age-related macular degeneration produces loss in the center of the field of vision as the retina’s center deteriorates.

RST-001 uses a photosensitivity gene to make new photosensors in retinal cells and restore vision.

It isn’t known whether Allergan would move RetroSense operations to Irvine.

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