The S&P 500 was flat at 3,086.02 in midday trading Friday.
The Dow Jones Industrial Average was down 0.1% to 27,646.03, while the Nasdaq rose 0.2% to 8,452.09.
The yield on a 10-year Treasury bond was down 0.4% to 1.92%.
Gold was off 0.3% to $1,463.
Crude oil pricing was up 0.2% to $57.24 a barrel.
San Clemente maker of glaucoma therapies Glaukos Corp. (NYSE: GKOS) was trading up 4.8% to $61.76 for a market value of $2 billion. The company earlier this week reported results for its third quarter ended September that beat consensus estimates on revenue and earnings.
Impac Mortgage Holdings Inc. (NYSE: IMH) fell 12% to $6.40 and a $133 million market. The Irvine-based lender yesterday reported third quarter revenue rose 33% to $25.8 million. The shares are still up more than double since July.