The S&P 500 was down 0.5% to 2,713.22; the markets closed at 10 a.m. today for the July 4th holiday.
The Dow Jones Industrial Average fell 0.5% to 24,174.82.
The Nasdaq declined 0.9% to 7,502.67.
The yield on a 10-year Treasury bond fell 1% to 2.84%
The price of gold climbed 1% to $1,254.
ChromaDex Corp. (Nasdaq: CDXC) in Irvine was up 10% to $4.06 and a $223 million market cap. Shares of the nutritional ingredients maker are up 26% since May 29.
Cryoport Inc. (Nasdaq: CYRX) climbed 3.6% to $16 and a $443 million market cap. Shares of the life sciences products shipper are up 138% since April 24. The company on May 3 reported first quarter revenue climbed 48% to $4 million.