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Orange County companies drew $188.2 million in venture capital funding in the first quarter, a 29% increase from the year-earlier period.

The total, the largest during a first-quarter since 2011, was spread over 16 businesses, compared with 11 last year, according to data from Dow Jones VentureSource.

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Healthcare companies accounted for six of the investments and about 71% of the dollar volume. Among them were Aliso Viejo-based glaucoma treatment startup AqueSys Inc., which raised $43.6 million in January; Irvine-based Axonics Modulation Technologies Inc., which had its first funding round of $32.6 million; and Sequent Medical Inc. in Aliso Viejo, which got $20 million in its later-stage funding.

Nearly $41 million went to five information-technology companies, including $20 million to Cylance Inc., an Irvine-based cyber-security software developer.

OC-based investors that made local investments in the latest quarter were Frost Data Capital in San Juan Capistrano and Versant Venture Management LLC in Newport Beach.