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Israel-based drug maker Teva Pharmaceutical Industries is eliminating 5,000 jobs, or about 10% of its global work force, in a cost-cutting bid.

Teva, which makes generic drugs, employs about 500 people in an Irvine plant. The drug maker didn’t specify where the job cuts were coming from.

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The drug maker added that it was going to cut assets that don’t fit its core business or fit its future.

Teva cut 20 jobs in Irvine earlier this year; 65 jobs last year and 156 in 2011. The 2011 cuts came about after an earlier year-long halt to production after it stopped making propofol, a sedative that gained notoriety in Michael Jackson’s death.

The drug maker got its Irvine plant in 2003 after it bought generic drug maker Sicor Inc.