Hoag Memorial Hospital Presbyterian and St. Joseph Health announced plans to form an affiliation and develop an integrated regional health network.

Executives of Newport Beach-based Hoag and Orange-based St. Joseph said they aim to “transform healthcare delivery” and become “a model for addressing some of the biggest challenges in American healthcare.”

The new regional affiliation will include Hoag and St. Joseph’s respective Southern California hospitals, a large doctor network, and numerous outpatient and urgent care facilities in Orange County and the High Desert.

Hoag is made up of its main Newport Beach hospital and a second campus in Irvine. St. Joseph Health’s local facilities include St. Joseph Hospital-Orange, Fullerton’s St. Jude Medical Center and Mission Hospital, with campuses in Mission Viejo and Laguna Beach. It also owns St. Mary Medical Center in Apple Valley.

St. Joseph’s hospital in Northern California, New Mexico and Texas are not expected to be part of the affiliation with Hoag.

Executives of both healthcare providers emphasized that Hoag and St. Joseph would retain their individual identities and faith affiliations. Hoag is affiliated with the Presbyterian church, while St. Joseph is a Catholic health system.

The plan to affiliate requires regulatory clearance from state Attorney General Kamala Harris’ office. The hospitals plan to apply for that in October and could require more than 100 days for a decision.