Orange County Business Journal

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Device Maker Ellipse in $410M Sale

Aliso Viejo-based medical device maker Ellipse Technologies Inc. will be sold to San Diego-based NuVasive Inc. in a deal worth up to $410 million.

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Care Facility Operator Names President

Irvine-based healthcare facilities operator Silverado named Shamim Wu president and chief operating officer, a new position.

2016 Preview: HEALTHCARE

Hospital affiliations, after being overshadowed by large deals involving Allergan Inc., which was based in Irvine, are poised to come back as a major activity to watch as 2016 begins.

2015 YEAR IN REVIEW: Healthcare

We selected Mussallem—chief executive of Irvine-based Edwards Lifesciences Corp. and a dean of the OC device sector—as the person to watch for 2015 for a variety of reasons, including the heart valve maker’s ascension to become the largest publicly traded healthcare company based here.

Griffin-American Purchase Builds in Growth Potential

REIT Completes Buy, Enters Senior Care Sector

Irvine-based Griffin-American Healthcare REIT III Inc. has completed its $1.1 billion buy of privately held Trilogy Health Investors LLC in Louisville, Ky.

Irvine’s Reputation Draws German Valve Maker

HEALTHCARE: JenaValve joins heart valve cluster here

Irvine’s reputation as a center for makers of transcatheter replacement heart valves has attracted a German company.

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Alphaeon Names Two Board Members

Irvine-based Alphaeon Corp. has named former New Mexico governor Bill Richardson and James Xiaodong Liu, chief executive of Hong Kong-based Sailing Capital Management to its board of directors.

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Alphaeon Names Two Board Members

Irvine-based Alphaeon Corp. has named former New Mexico governor Bill Richardson and James Xiaodong Liu, chief executive of Hong Kong-based Sailing Capital Management to its board of directors.

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Ex-Allergan President Tapped by DC Drug Developer

Chase Pharmaceuticals Corp. said that it has appointed Douglas Ingram, a former president of Allergan Inc., which was based in Irvine, as its chief executive.

Masimo, China Customer Settle Over Patents, Devices

Companies Also Agree Not to Sue Each Other

Irvine-based Masimo Corp. stopped in its tracks a potential patent battle with one of its original equipment manufacturing customers.

Allergan Boss: Role for Irvine After Mega Deal

HEALTHCARE: Key to Pfizer’s plan to carve out ‘innovative’ lines

Irvine appears set to remain a hub for a core part of Pfizer PLC after it acquires Allergan PLC in an expected $155 billion deal that would create the world’s largest drugmaker, with more than $60 billion in sales.

Affiliation Commands Attention

Proposed Deal With Providence on Front Burner at St. Joseph

Jim Watson’s work on a pair of complex affiliations for his employer has caught the eyes of his peers in Orange County’s legal community.

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St. Joseph Health Signs Agreement with Providence

Irvine-based St. Joseph Health said today it signed a definitive agreement with Renton, Wash.-based Providence Health and Services.

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St. Joseph Health Signs Agreement with Providence

Irvine-based St. Joseph Health said today it signed a definitive agreement with Renton, Wash.-based Providence Health and Services.

OCTANe Plans Continued Support of LaunchPad Businesses

Will Expand Initiative To Connect Ideas, Investors

Panel discussions and business plan competitions weren’t the only agenda items on deck at the Medical Device & Investor Forum held this month by Aliso Viejo-based group OCTANe.

Alphaeon Pays $59M for Device Maker

HEALTHCARE: Adds software firm on undisclosed terms

Alphaeon Corp. keeps on making deals.

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ICU Medical Shutters Slovakia Plant

San Clemente-based ICU Medical Inc. will close its manufacturing plant in Vrable, Slovakia, and cut 265 jobs, according to a Securities and Exchange Commission filing.

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Alphaeon to Buy Laser Maker

Irvine-based Alphaeon Corp. said today that it would buy Lensar Inc. for up to $59 million.

Irvine Front and Center for Allergan R&D

HEALTHCARE: Kybella seen as next ‘pipeline in a product’ for drugmaker

Allergan PLC’s operations in Irvine appear poised to remain front and center in the drugmaker’s research and development endeavors.

ICU Medical Looks to Increase Lucrative OEM Work

Manufacture of Parts For Others ‘Outperformed’

Making parts for other manufacturers is paying off for San Clemente-based ICU Medical Inc.

Saunders Touts Innovation Amid Allergan-Pfizer Chatter

HEALTHCARE: Also talks up leadership on aesthetics

Brent Saunders, chief executive and architect of the “new” Allergan PLC, stayed on the go during a visit to Orange County earlier this month.

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Judge: Valeant, Ackman Must Face Insider Suit on Allergan

U.S. District Court Judge David Carter of Santa Ana has declined a request from Valeant Pharmaceuticals International Inc., led by Chief Executive Mike Pearson, and activist investor Bill Ackman to dismiss a lawsuit accusing them of insider trading in shares of Allergan Inc.

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Bloomberg: Pfizer, Allergan See Saunders as CEO

Drug makers Allergan PLC and Pfizer Inc. are eyeing a plan to make current Allergan Chief Executive Brent Saunders head of a combined company if they reach a takeover deal, Bloomberg Business reported today, citing unnamed sources.

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Quality Systems Names Chairman

Irvine-based Quality Systems Inc. named Jeffrey Margolis its new chairman.

Clearance for 1 Masimo Device, Good News on 2nd

Oximeter OK’d, EMMA, SET Studies Presented

Masimo Corp., an Irvine-based maker of patient monitors, finished out October on a fast pace.

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Quality Systems Names Margolis Chairman

Irvine-based Quality Systems Inc. said today that Jeffrey Margolis is its new chairman.

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ICU Medical Beats Street

San Clemente-based ICU Medical Inc. today reported an adjusted third-quarter profit that beat analysts’ forecasts.

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Masimo Surpasses Expectations

Irvine-based Masimo Corp. today reported third-quarter results that exceeded Wall Street expectations.

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ChromaDex in Proctor & Gamble Deal

Irvine-based ChromaDex Corp. said today it signed a joint development deal with Cincinnati-based conglomerate Proctor & Gamble Co.

Chinese Buyer for Life Sciences Supplier

Santa Ana-based MP Biomedicals LLC was sold to Valiant Co. in China for about $134 million.

Endologix Pays Twice for Fellow Device Maker

HEALTHCARE: $211M deal trims market capitalization by 30% in day

Endologix Inc.’s bid to grow market share through a newly struck deal to acquire a competitor appears to have set investors in the Irvine-based medical device maker on edge.

OC Operations Help Danaher Boost Q3 Performance

Local Units Part of 23% Revenue Hike on Dental

Units with an Orange County presence helped drive improved financial performance for Danaher Corp.’s third quarter, according to company executives.

Direct Flow Focused on Trio of Strategies for Growth

HEALTHCARE: Europe rollout, Salus trial, mitral valves in plan

Medical device maker Direct Flow Medical Inc., which maintains a Lake Forest manufacturing hub, is pursuing a three-pronged plan for progress under new leadership.

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Endologix Shares Dive

Shares of Irvine-based medical device maker Endologix Inc. plummeted today on news of a third-quarter loss.

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Edwards Beats, Shares Rise

Irvine-based Edwards Lifesciences Corp. reported financial results today that exceeded expectations and sent its shares up in after-hours trading.

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China Co. Buys Milan Panic's Biomed Firm

Santa Ana-based MP Biomedicals LLC has been sold to Valiant Co., Ltd., in China for about $134 million.

Peregrine Broadens AstraZeneca Cancer Clinical Pact

Collaboration Will Include Second Later-Stage Trial

Tustin-based drug developer Peregrine Pharmaceuticals Inc. is expanding its relationship with British drugmaker AstraZeneca PLC.

St. Joseph Moves Investment Recipient to Irvine

HEALTHCARE: Joins software work with that of other startups

St. Joseph Health has moved the technology development arm of a company it invested in from Colorado to Irvine.

Medical, Diagnostic Product Tester Expands OC Digs

SERVICES: CSA Group hopes to win more customers

Toronto, Canada-based CSA Group is opening a new laboratory in Irvine with the intent of winning more business from the area’s medical device and diagnostic products makers.

Ellipse Aims to Join Wave of 2015 Healthcare IPOs

HEALTHCARE: AV device maker to sell $75M in shares

Ellipse Technologies Inc. is gearing up to test the initial-public-offering waters.

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Allergan Wraps $300M AqueSys Deal

Allergan PLC finalized its purchase of Aliso Viejo-based AqueSys Inc. for $300 million plus milestone payments.

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Edwards Works With CareFusion

Irvine-based cardiovascular device maker Edwards Lifesciences Corp. said today that it signed a deal with San Diego-based CareFusion, a BD company, to enable a pair of their respective devices to work together.

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Quality Systems Sells Hospital Unit

Irvine-based Quality Systems Inc. sold the hospital software division of its NextGen Healthcare subsidiary to Reston, Va.-based QuadraMed Affinity Corp. A purchase price was not disclosed.

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Allergan Shares Briefly Halted

Trading of shares in Allergan PLC, whose Botox and eye drug hubs are in Irvine, was briefly halted today and are down in midday trading on news involving rival Valeant Pharmaceuticals International Inc.

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Ellipse Files for IPO

Aliso Viejo-based Ellipse Technologies Inc. filed for an initial public offering with the Securities and Exchange Commission to raise up to $75 million.

Masimo Executives Outline Positions for Growth

Report: Company Could Develop ‘Third Pillar’

Irvine-based Masimo Corp. executives recently took to the road to share the patient monitor maker’s story with investors as it moves through the eighth year of its 10-year business plan.

Allergan’s Irvine Hub Poised for Boost on Appeal to Other Half

HEALTHCARE: Newly acquired double-chin drug hot, mostly for men

The Botox Cosmetic line and other products overseen by Allergan PLC’s hub in Irvine have long been favorites among well-heeled women.

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FDA Clears Additional Use for Edwards Sapien XT

Irvine-based Edwards Lifesciences Corp. said today that the Food and Drug Administration approved its Edwards Sapien XT replacement heart valve for aortic valve-in-valve procedures.

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Allergan’s Kythera to Lay Off 117

Kythera Biopharmaceuticals Inc. is cutting 117 workers – or more than half its workforce – after its acquisition earlier this month by Dublin, Ireland-based drug maker Allergan PLC in an all-cash deal valued at some $2.1 billion, according to a state filing.

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St. Joseph Health Puts $10M in Software Maker

Irvine-based St. Joseph Health has invested $10 million to expand its partnership with Boulder, Colo.-based Datu Health.

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