Orange County Business Journal

Stem Cell Deal Puts Manufacturing Might on Keirstead’s Side

HEALTHCARE: Pioneer’s startup to operate here as unit of N.Y. owner

Manufacturing is the key to the vast potential of stem cells.

Analysts Downplay Covidien Aneurysm Devices Recall

Coating Could Come Off, Lead to Stroke or Death

Covidien PLC’s voluntary recall of more than 600 Orange County-manufactured aneurysm devices will be a slight hit on its top line, according to industry watchers.

Tease photo

Allergan Acquires Dermal Filler Candidate

Irvine-based Allergan Inc. acquired a dermal filler candidate from Menlo Park-based incubator TauTona Group.

Tease photo

Allergan Acquires Dermal Filler Candidate

Irvine-based Allergan Inc. said today that it acquired a dermal filler candidate from Menlo Park-based incubator TauTona Group.

Tease photo

California Stem Cell to Be Bought by NeoStem

Irvine-based California Stem Cell Inc. said today that it was being acquired by NeoStem Inc. in a stock and cash deal that potentially could be worth $124 million.

Questcor Expected to Stay After $5.6B Sale

HEALTHCARE: Anaheim company to continue operations as own unit

It appears that the local operations of Questcor Pharmaceuticals Inc. would remain intact in the wake of Mallinckrodt PLC’s $5.6 billion proposed buyout of the Anaheim-based drug maker—the largest deal so far in what’s shaping up to be a busy year for mergers and acquisitions involving Orange County-based companies.

Edwards Gets European Clearance for Heart Valve

Says More Can Get Less Invasive Procedure Now

Irvine-based Edwards Lifesciences Corp.’s run of good news continued this month.

Tease photo

Hoag Extends Obligation on Women’s Health Services

Hoag Memorial Hospital Presbyterian has entered into a voluntary agreement with state Attorney General Kamala Harris’ office to extend its obligation to provide women’s health services.

Pyott’s Place: Not Big Pharma

CEO: Cash-Pay Lines, Less Bureaucracy Set Allergan Apart

Call Allergan Inc. the biggest publicly traded company in Orange County. Just don’t call it “Big Pharma.”

Regulators Accept Avanir’s New-Drug Application

AVP-825 Drug-Device Combo to Treat Migraines

Aliso Viejo-based Avanir Pharmaceuticals Inc. wrapped up last month in a busy fashion.

Edwards Gets Taste of Better Days on Comparison Trial

HEALTHCARE: Shares up 13% this year after rugged 2013

Investors are once again taking a shine to Irvine-based Edwards Lifesciences Corp. after a tough 2013.

Biolase Shareholder in Mood for Fight

HEALTHCARE: East Coast investor nominates 4 to board

Irvine-based medical device maker Biolase Inc. is facing the prospect of a proxy fight with its largest shareholder.

Tease photo

Hoag Extends Obligation on Women’s Health Services

Hoag Memorial Hospital Presbyterian has entered into a voluntary agreement with state Attorney General Kamala Harris’ office to extend its obligation to provide women’s health services.

Startup Device Maker Raises $32.5M

Irvine-based Axonics Modulation Technologies Inc. completed a $32.5 million first round of financing.

Questcor Pharmaceuticals Responds to Recent ‘Bear Raid’

Acthar Maker Says Shorts Have Caused Volatility

Questcor Pharmaceuticals Inc., one of Orange County’s more volatile public companies, recently released a lengthy federal filing addressing what it characterized as a “bear raid” by short sellers.

$32.5 Million for Irvine Device Maker

Irvine-based Axonics Modulation Technologies Inc. said today it completed a $32.5 million first round of financing.

Sonendo Raises $10 Million

Sonendo Inc., a Laguna Hills-based dental device company, closed a $10 million venture debt financing with Alexandria, Va.-based Oxford Finance LLC.

Sonendo Raises $10 Million

Sonendo Inc., a Laguna Hills-based dental device company, closed a $10 million venture debt financing with Alexandria, Va.-based Oxford Finance LLC.

$32.5 Million for Irvine Device Maker

Irvine-based Axonics Modulation Technologies Inc. said today it completed a $32.5 million first round of financing.

Device Designer to Stay Local Under New Owner

HEALTHCARE: Sees benefit in Illinois company’s size

An Irvine design and engineering firm that develops products for medical device and biotech companies has been sold to a larger competitor.

UK Device Maker Eyes Offering Here

HEALTHCARE: Lombard’s US operations in Irvine

A British medical device maker that has its U.S. headquarters in Irvine is seeking its fortune in the U.S.

Allergan Growth Outlook ‘Noteworthy Exception’

Among Best Large-Cap Growth Prospects

Irvine-based Allergan Inc. is offering “a precious commodity” for pharmaceutical investors—growth, according to one analyst.

Tease photo

Device Maker Presbia Files for IPO

Irvine-based eye device maker Presbia PLC on Thursday filed a registration statement with the Securities and Exchange Commission to offer $90 million in common stock.

Tease photo

Device Maker Presbia Files for IPO

Irvine-based eye device maker Presbia PLC today filed a registration statement with the Securities and Exchange Commission to offer $90 million in common stock.

AtheroNova Offering $15M in Stock, Plans Exchange Move

Irvine-based AtheroNova Inc. has filed papers with the Securities and Exchange Commission to sell $15 million worth of common stock and move its listing to the New York Stock Exchange.

AtheroNova Offering $15M in Stock, Plans Exchange Move

Irvine-based AtheroNova Inc. has filed papers with the Securities and Exchange Commission to sell $15 million worth of common stock and move its listing to the New York Stock Exchange.

St. Joe’s Cuts Reflect New Dynamics for OC Hospitals

HEALTHCARE: Some service shifts to CHOC, Hoag Irvine

Recent layoffs at one of Orange County’s bigger hospitals appear to be a reaction to a number of changes in the local hospital landscape.

Gores Group Backs Device Maker’s Buy

HEALTHCARE: San Clemente company buys in Slovenia

A San Clemente-based medical laser maker has reached into Eastern Europe with help from a private equity firm in Los Angeles.

Irvine Medical Device Maker Seeks IPO

Lombard Medical Inc., a British medical device maker with U.S. headquarters in Irvine, filed a registration statement with the Securities and Exchange Commission for an $80 million initial public offering on the Nasdaq exchange.

British Heart Team Uses Edwards Valve in Implants

Doctor Said Device Could Extend, Improve Lives

Edwards Lifesciences Corp. recently hit another milestone with one of its less-invasive heart valves.

Hoag Adds Services in 50,000-SF Expansion in HB

HEALTHCARE: Addition to existing center to open in April

Hoag Memorial Hospital Presbyterian is doubling its presence in Huntington Beach, where it plans to provide “integrated care” through a mix of services.

Tease photo

Device Maker Plans $80M U.S. IPO

Lombard Medical Inc., a British medical device maker with U.S. headquarters in Irvine, has filed a registration statement with the Securities and Exchange Commission for an $80 million initial public offering on the Nasdaq exchange.

Tease photo

Device Maker Plans $80M U.S. IPO

Lombard Medical Inc., a British medical device maker with U.S. headquarters in Irvine, has filed a registration statement with the Securities and Exchange Commission for an $80 million initial public offering on the Nasdaq exchange.

Tease photo

FDA Clears Pair of Irvine Company’s Medical Devices

Ellipse Technologies Inc., an Irvine medical device maker, said the Food and Drug Administration recently gave it marketing clearance for a pair of its products.

Tease photo

FDA Clears Pair of Irvine Company’s Medical Devices

Ellipse Technologies Inc., an Irvine medical device maker, said the Food and Drug Administration recently gave it marketing clearance for a pair of its products.

Medical Device Tax Repeal Bid Emerges in New Form

Latest in String of Efforts To Kill 2.3% Revenue Tax

A longtime effort to repeal a federal tax on medical device makers’ revenue is bubbling up again.

UCI Cancer Center Adds Trial, Treatment Options

HEALTHCARE: $5M paves way for more advanced trials

A new center for cancer research and clinical trials at the University of California, Irvine, has the potential to give patients who want to use advanced therapies a chance to stay in Orange County for treatments.

Tease photo

Smile Brands Names New Chief Executive

Irvine-based Smile Brands Group Inc. has appointed Dan Wechsler as its president and chief executive.

Tease photo

Ensign Buys Arizona Nursing Home

Mission Viejo-based nursing home operator Ensign Group Inc. said today that it bought Horizon Post-Acute and Rehabilitation Center in Glendale, Ariz. A purchase price wasn’t disclosed.

Tease photo

Ensign Buys Arizona Nursing Home

Mission Viejo-based nursing home operator Ensign Group Inc. said today that it bought Horizon Post-Acute and Rehabilitation Center in Glendale, Ariz. A purchase price wasn’t disclosed.

‘Cosmeceutical’ Pioneer Sees Fast Growth on ZO Line

HEALTHCARE: Irvine skincare line at $20M, 55 workers

Irvine-based ZO Skin Health Inc. wants to redirect women from the cosmetic counter to their doctor’s office.

Allergan Ups Retinal Disease R&D With Collaboration

Will Work With Voyant on Possible New Drugs

Irvine-based Allergan Inc. is adding to its programs for potentially treating age-related macular degeneration.

Tease photo

Questcor Shares Fall on FDA News

Anaheim-based Questcor Pharmaceuticals Inc.’s shares fell today after the Food and Drug Administration acknowledged that it was reviewing materials related to the company’s primary drug, H.P. Acthar Gel.

Masimo Gets Good Analyst Grades for Long Term

Still Uncertainty Over Covidien Royalty Payments

Irvine-based patient monitor maker Masimo Corp.’s long-term growth prospects remain attractive, an analyst said this month.

MemorialCare Gears Up for Healthcare Changes

HEALTHCARE: Promotions, new hires reflect reform’s effects

MemorialCare Health System is remaking its front office with an eye on healthcare reform.

Tease photo

Biolase Signs 3-D Printer Deal, Shares Rise

Irvine-based Biolase Technology Inc.’s stock jumped in the double digits Thursday after it signed a distribution deal for 3-D printers.

Tease photo

Biolase Signs 3-D Printer Deal, Shares Rise

Irvine-based Biolase Technology Inc.’s stock jumped in the double digits today after it signed a distribution deal for 3-D printers.

Kiani’s Patient Safety Bid Gains Look of Movement

HEALTHCARE: More companies, hospitals join Masimo-led initiative

More companies and hospitals are being drawn to the patient safety movement spearheaded by the chief executive of Irvine-based patient monitor maker Masimo Corp.

Allergan Spends More to Market Established Brands

Advertising Budget 13% Higher Than 2013’s

Irvine-based Allergan Inc. may be on the hunt for new products, both internally and externally, but it’s still working its core brands by investing in advertising campaigns, according to Chief Executive David Pyott.

Tease photo

Masimo’s Q4 Profit in Line, Misses on Revenue

Irvine-based medical device maker Masimo Corp. on Thursday posted a fourth-quarter profit in line with Wall Street, while revenue missed expectations.

Prev