The S&P 500 was down 0.1% in midday trading to 23,135.40.

The Dow Jones Industrial Average fell 0.1% to 23,135.57.

The NASDAQ dropped 0.5% to 6,592.91.

The yield on a 10-year Treasury bond declined 0.8% to 2.32%

The price of gold was up 0.6% to $1,290.

MANUFACTURING

Kaiser Aluminum Corp. (NASDAQ: KALU) was down 5.6% to $98.35 and a $1.7 billion market cap. The metals maker missed analyst expectations in a quarterly report yesterday after markets closed.

HEALTHCARE

Spectrum Pharmaceuticals Inc. (NASDAQ: SPPI) was down 5% to $18.75 and a $1.7 billion market cap. The drug developer closed 40% higher yesterday after reporting positive results of a clinical trial.