The S&P 500 was off 0.52% to 1,713.39 in afternoon trading Friday.
The Dow Jones industrial average fell 0.68% to 15,530.65, while the Nasdaq slipped 0.20% to 3,781.90.
The yield on a 10-year Treasury bond was off 0.91% to 2.72%.
The price of gold was down 2.66% to $1,332.90 per ounce.
Anaheim-based drug maker Questcor Pharmaceuticals Inc.'s shares continued to fall on Friday, down about 8% to $55.79. The volatile stock was trading at unusually high volume, about three times its average, as company watchers speculate on stock options expiring today.
Questcor Director Virgil Thompson sold off 5,000 shares earlier this week, according to a Securities and Exchange Commission filing.
The company, which had a recent market value of $3.31 billion, is still up more than 130% so far this year.
Homebuilders were generally down on Friday with Irvine-based Standard Pacific Corp.’s shares off the most among local companies.
Standard Pacific was down about 3% to $7.97 for a market value of $2.77 billion.
Newport Beach-based William Lyon Homes and TRI Pointe Homes Inc. of Irvine were both down about 1% to recent market values of $670.55 million and $472.47 million, respectively.