Ista Pharmaceuticals Inc. said Wednesday that its stockholders have approved the Irvine-based drug maker’s $500 million takeover by Rochester, N.Y.-based Bausch & Lomb Inc.

Ista, which makes eye-care drugs, said 79% of its outstanding shares were voted to approve the acquisition by Bausch. The transaction was expected to close by the end of today.

For more on this story, see the June 11 edition of the Business Journal.